Eberhard Karls University of Tübingen is a leading authority in vascular biology. Founded 1477, the university enrols around 22.000 students. The Department of Physiology is dedicated to translation of molecular mechanisms into whole animal and human physiology; it is experienced with in vitro and in vivo models of cardiac and vascular pathophysiology. Cardiovascular research at the institute is focused on cardiac and vascular fibrosis as well as calcification and vasculopathy in chronic kidney disease.

Within sysVASC, Eberhard Karls University of Tübingen will contribute data acquisition in vascular biology and perform inference studies.

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Prof. Florian Lang, MD 

Florian Lang is a highly recognized physiologist and is currently the 4th most cited in Europe. He has served as head of the physiology department at the Eberhard Karls University Tuebigen since 1992, and is editor of a number of journals including: Kidney and Blood Pressure Research, Nephron, and Cellular Physiology and Biochemistry, among others. Florian Lang has made several seminal observations on the regulation of ion channels and transporters relevant for proper cardiovascular function.

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1 Voelkl, J., et al. (2013). Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest. 123, 812–822.

2 Borst, O., et al. (2012). The Inflammatory Chemokine CXC Motif Ligand 16 Triggers Platelet Activation and Adhesion Via CXC Motif Receptor 6–Dependent Phosphatidylinositide 3-Kinase/Akt Signaling. Circ Res. 111, 1297-307.

3 Salker et al. (2011). Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nat Med. 17, 1509-13.

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