The French National Institute of Health and Medical Research (INSERM) is a renowned centre in fibrosis research and animal model systems. Founded in 1964, INSERM is a public, scientific and technological institute which operates under the joint authority of the French Ministry of Health and French Ministry of Research. INSERM’s U1048 (Institute of Cardiovascular and Metabolic Diseases (12MC)) in Toulouse focuses on metabolic, cardiovascular and renal diseases. The main feature of the 12MC is the collaboration of basic scientists and clinicians working on metabolic risk factors such as obesity, diabetes and their cardiovascular complications (thrombosis, atherosclerosis, cardiac and renal failure).

Within sysVASC, INSERM will contribute pre-clinical animal models, and perform physiological phenotyping.

Joost Schanstra

© biolution GmbH


Joost P Schanstra, PhD

Joost Schanstra is director of research at the Institute of Metabolic and Cardiovascular Research (INSERM U1048) and an expert in clinical proteomics in renal and cardiovascular disease with key papers in Nature Medicine and Science Translational Medicine. He has longstanding experience with national as well as international projects.

INSERM_mouse vessel with plaques

© Joost-Peter Schanstra



1 Klein J., et al. (2012). The KUPKB: a novel Web application to access multiomics data on kidney disease. FASEB J. 26, 2145-53.

2 Dominiczak A.F., et al. (2010). Systems biology to battle vascular disease. Nephrol Dial Transplant. 25, 1019-22.

3 Klein J., et al. (2010). Blockade of the kinin B 1 receptor ameloriates glomerulonephritis. J Am Soc Nephrol. 21, 1157-64.

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